###147852369$$$_RedirectToLoginPage_%%%963258741!!!

Dinesh Ahirwar

Dinesh Ahirwar

Assistant Professor
school
Phd. Sanjay Gandhi Postgraduate Institute of Medical Sciences
biotech
Host-tumor interaction, Drug resistance, Immunotherapy
call
0291 280 1222
language
Web Profile

Dinesh Kumar Ahirwar

I am an Assistant Professor in the Department of Bioscience and Bioengineering at IIT Jodhpur. I have also served as a Research Assistant Professor at the Department of Pathology, The Ohio State University, USA from 2019 to 2022. I am a recipient of Pelotonia Postdoctoral Fellowship, The Ohio State University, USA. 

The focus of my research group is to develop diagnostic and prognostic biomarkers and drug targets for lung cancer using multi-omics approaches. We also perform drug testing in clinically relevant patient-derived xenografts in humanized mouse models and tumor organoids. 

In one of our projects, we are developing induced-Pluripotent Stem Cells (iPSCs)-derived lung organoids for studying the molecular mechanisms of silica dust-induced Silicosis disease, which is an occupational hazard for sandstone miners in the local area.

We also perform drug repurposing studies to identify drug combinations capable of improving the efficacy of existing chemotherapies and immunotherapies for drug-resistant lung cancer patients. My previous research showed that tumor-associated macrophages can be activated against breast and lung cancers. This research has potential to develop novel immune-based therapies for cancer patients. The long term goal of my research is to improve the health status of lung cancer and Silicosis patients.

 

arrow_downward