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Dibyendu Kumar Sasmal

Dibyendu Kumar Sasmal

Associate Professor
school
Ph.D.: Indian Association for the Cultivation of Science
biotech
Experimental Physical Chemistry, Fluorescence Spectroscopy and Imaging, Biophysical Chemistry
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0291 280 1314
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Web Profile

Biography

Dr. Dibyendu K. Sasmal is an Associate Professor in the Department of Chemistry at the Indian Institute of Technology Jodhpur, where he has been serving since July 2023, following his tenure as an Assistant Professor from 2019 to 2023. His academic journey began with a Bachelor of Science (Honors) in Chemistry from Medinipur College, Vidyasagar University, in 2005, followed by a Master of Science (M.Sc.) in Chemistry with a specialization in Physical Chemistry in 2007. He earned his Ph.D. in Physical Chemistry in 2012 from the Indian Association for the Cultivation of Science, Kolkata, under the guidance of Professor Kankan Bhattacharyya. Post-Ph.D., he conducted postdoctoral research at Bowling Green State University, Ohio, USA, with Professor H. Peter Lu, followed by research at the Pritzker School of Molecular Engineering, University of Chicago, under Professor Jun Huang, and later at the Center for Nanoscale Materials, Argonne National Laboratory, Illinois, with Professor Tijana Rajh.

Research

Dr. Sasmal and his group is interested to understand complex interplay among structure, function, and dynamics of bio-molecules present either in condensed phase or cellular environment at single molecular level in real-time. Conventional ensemble methods can only give information related to molecular function which are average of property with respect to time. However, single-molecule spectroscopy has an unique capabilities for distinguishing molecular properties with spatiotemporal resolution of sub-nano meter and pico-seconds. Their approach is highly interdisciplinary combining molecular spectroscopy, molecular biology, optics and advanced fluorescence microscopy. The group is currently investigating the pattern of conformational dynamics of DNA, protein and RNA. They are also trying to understand how immune cells distinguish between self and foreign antigens at single molecule level in real time. Drug-protein interaction in condensed phase, and development of quantum dot based drug carrier, fluorescence correlation spectroscopy (FCS) and fluorescence lifetime imaging microscopy (FLIM) are also topic of research for this group. 

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