Dibyendu Kumar Sasmal

Dibyendu Kumar Sasmal
Associate ProfessorBiography
Dr. Dibyendu K. Sasmal is an Associate Professor in the Department of Chemistry at the Indian Institute of Technology Jodhpur, where he has been serving since July 2023, following his tenure as an Assistant Professor from 2019 to 2023. His academic journey began with a Bachelor of Science (Honors) in Chemistry from Medinipur College, Vidyasagar University, in 2005, followed by a Master of Science (M.Sc.) in Chemistry with a specialization in Physical Chemistry in 2007. He earned his Ph.D. in Physical Chemistry in 2012 from the Indian Association for the Cultivation of Science, Kolkata, under the guidance of Professor Kankan Bhattacharyya. Post-Ph.D., he conducted postdoctoral research at Bowling Green State University, Ohio, USA, with Professor H. Peter Lu, followed by research at the Pritzker School of Molecular Engineering, University of Chicago, under Professor Jun Huang, and later at the Center for Nanoscale Materials, Argonne National Laboratory, Illinois, with Professor Tijana Rajh.
Research
Dr. Sasmal and his group is interested to
understand complex interplay among structure, function, and dynamics of bio-molecules
present either in condensed phase or cellular environment at single molecular
level in real-time. Conventional ensemble methods can only give information
related to molecular function which are average of property with respect to
time. However, single-molecule spectroscopy has an unique capabilities for distinguishing
molecular properties with spatiotemporal resolution of sub-nano meter and pico-seconds.
Their approach is highly interdisciplinary combining molecular spectroscopy, molecular
biology, optics and advanced fluorescence microscopy. The group is currently
investigating the pattern of conformational dynamics of DNA, protein and RNA. They
are also trying to understand how immune cells distinguish between self and
foreign antigens at single molecule level in real time. Drug-protein
interaction in condensed phase, and development of quantum dot based drug carrier,
fluorescence correlation spectroscopy (FCS) and fluorescence lifetime imaging
microscopy (FLIM) are also topic of research for this group.